Ribavirin
CAS number 36791-04-5
Molecular weight C8H12N4O5 = 244.2
Assay > 98 %
Ribavirin is a synthetic nucleoside analogue structurally related to guanine. Ribavirine inhibits the replication of a wide range of RNA and DNA viruses. The antiviral mechanism of action of Ribavirin is not fully defined, but relates to alteration of cellular nucleotide pools and inhibition of viral mRNA synthesis. Intracellular phosphorylation of ribavirin into phosphate derivatives is mediated by host cell enzymes. Ribavirin monophosphates competatively inhibit cellular inosine-5’-phosphate dehydrogenase and interfere with the synthesis of guanosine triphospha-te (GTP) and thus nucleic acid synthesis in general. Ribavirin triphosphate also competively inhibits the GTP dependent 5’-capping of viral mRNA.
Storage condition
- Store at room temperature
- Freely soluble in water
Hazard statements
- H360 May damage fertility or the unborn child
Precautionary statements
- P201 Obtain special instructions before use
- P281 Use personal protective equipment as required
- P308 IF exposed or concerned:
- P313 Get medical advice/attention
| Filename | Language | File size |
|---|---|---|
| R0182_GB.pdf | English | 488 KB |
| R0182_NL.pdf | Nederlands | 493 KB |
| R0182_DE.pdf | Deutsch | 507 KB |
| R0182_FR.pdf | Français | 497 KB |
| R0182_ES.pdf | Español | 492 KB |
| R0182_IT.pdf | Italiano | 492 KB |
| R0182_PL.pdf | Polish | 506 KB |
| R0182_KO.pdf | Korean | 556 KB |
| R0182_DA.pdf | Danish | 491 KB |
| R0182_SV.pdf | Swedish | 491 KB |
| R0182_FI.pdf | Finnish | 489 KB |
| R0182_CS.pdf | Czech | 501 KB |
| R0182_EL.pdf | Greek | 518 KB |
| R0182_TR.pdf | Turkish | 503 KB |