T0154
Trimethoprim
CAS number 738-70-5
Molecular weight C14H18N4O3 = 290.3
Assay > 98.5 %
Trimethoprim is active against gram-negative and gram-positive aerobic bacteria. The antibioticum is a dihydrofolate reductase inhibitor. It inhibits the conversion of dihydrofolic acid to tetrahydrofolic acid, which is necessary for the synthesis of amino acids, purines, thymidines and ultimately DNA synthesis. Resistance may develop very fast.
Storage condition
- Store dry at room temperature
- Soluble in propyleneglycol
Hazard statements
- H302 Harmful if swallowed
- H361 Suspected of damaging fertility or the unborn child
- H372 Causes damage to organs through prolonged or repeated exposure
Precautionary statements
- P201 Obtain special instructions before use
- P264 Wash
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P308 IF exposed or concerned:
- P313 Get medical advice/attention
- P314 Get Medical advice/attention if you feel unwell